​PRINCIPAL INVESTIGATOR

2024

• Wu, L. Y., Hung, W.L., Cheng, L. Y., Su, Z. Y., Hsu, B. Y. Protective effects of water extract of Chenopodium formosanum koidz husk on metabolic syndrome. Preventive Nutrition and Food Science. Accepted.

• Chin, W. S., Chuang, Y. N., Hung, W. L., Say, Y. H., Chien, L. C., Chen, Y. C., Kao, H. C., Luo, M. P., Chang, C. H., Liao, K. W. Association between urinary paraben concentrations and early renal impairment in young adults in Taiwan. Exposure and Health. In press.

• Chin, W. S., Hung, W. L., Say, Y. H., Chien, L. C., Chen, Y. C., Lo, Y. P., Liao, K. W. The influence of exposure to inorganic arsenic and other arsenic species on early renal impairment among young adults in Taiwan. Environmental Pollution 2024 125090.

• Hsiao, Y. W., Hisa, S. M., Pan, M. H., Ho, C.T., Hung, W. L.* Berry anthocyanins prevent a-dicarbonyls and advanced glycation end product formation in phosphate-buffered saline-based model systems, cookie and ground pork. Journal of Food Science 2024, 89, 3745-3758. 

2023

• Hung, W. L, Chiu, T. H., Wei, G. J,, Pan, M. H., Ho, C. T., Hwang, L. S. Neuroprotective effects of nobiletin and tangeretin against amyloid b1-42-induced toxicity in cultured primary rat neurons. Nutrire 2023, 48:56. 

• Lin, Y. Y., Huang, S. F., Liao, K. W., Ho, C. T., Hung, W. L.,* Quantitation of a-dicarbonyls, lysine- and arginine-derived advanced glycation end products in commercial canned meat and seafood products. Journal of Agricultural and Food Chemistry 2023, 71, 6727-6737. 

• Ren R., Zhao, A. Q., Chen, L., Wu, S., Hung, W. L.,* Wang, B.* Therapeutic effect of Lactobacillus plantarum JS19 on mice with DSS-induced acute and chronic ulcerative colitis. Journal of the Science of Food and Agriculture, 2023, 103, 4143-4156.

2022

• Chen, Y. T., Lin, Y. Y., Pan, M. H., Ho, C. T., Hung, W. L.* Inhibitory effects of rooibos (Aspalathus linearis) against reactive carbonyl species and advanced glycation end product formation in a glucose-bovine serum albumin and cookies. Food Chemistry X, 2022, 100515. 

2021

• Hsu, B. Y., Chen, C. H., Lu, T. J., Pan, M. H., Ho, C. T., Hwang, L. S., Hung, W. L.* Bioconversion of ginsenosides in American ginseng extraction residue by fermentation with Ganoderma lucidum improves insulin-like glucose uptake in 3T3-L1 adipocytes. Fermentation 2021, 7, 297.

• Hung, W. L., Hsiao, Y. T., Chiou, Y. S., Nagabhushanam, K., Ho, C. T., Pan, M. H. Hepatoprotective effect of piceatannol against carbon tetrachloride-induced liver fibrosis in mice. Food & Function, 2021, 12, 11229.

2020

• Reuss, L., Feng, S., Hung, W. L., Yu, Q., Gmitter, F., Wang, Y. Analysis of flavor and other metabolites in lemon juice (Citrus limon) from Huanglongbing-affected trees grafted on different rootstocks. Journal of Food and Drug Analysis 2020, 20228, 261-272.

• Dahl, W., Hung, W. L., Ford, A., Suh, J. H., Auger, J., Nagulesapillai, V., Wang, Y. In older women, a high-protein diet including animal-sourced foods did not impact serum levels and urinary excretion of trimethylamine-N-oxide. Nutrition Research, 2020, 78, 72-81

• Hung, W. L., Ho, C. T., Pan, M. H. Targeting the NLRP3 inflammasome in neuroinflammation: health promoting effects of dietary phytochemicals in neurological disorders. Molecular Nutrition and Food Research. 2020, 64. 1900550.

2019

• Tung, Y. C., Chou, Y. C., Hung, W. L., Cheng, A. C., Yu, R. C., Ho, C. T., Pan, M. H. Polymethoxyflavones: Chemistry and molecular mechanisms for cancer prevention and treatment. Current Pharmacology Reports 2019, 5, 98-113.

• Wang, S., Pan, M. H., Hung, W. L., Tung, Y. C., Ho, C. T. From white to beige adipocytes: therapeutic potential of dietary molecules against obesity and their molecular mechanisms. Food & Function, 2019, 10, 1263-1279.

• Yao, L., Yu, Q., Huang, M., W. L. Hung., Grosser, J., Chen, S., Wang, Y., Gmitter, F. Proteomic and metabolomic analyses provide insight into the off-flavour of fruits from citrus trees infected with ‘Candidatus Liberibacter asiaticus’. Horticulture Research 2019, 6, 31.

• Li, G. J.; Wu, H. J.; Wang. Y.; Hung, W. L.; Rouseff, R. Determination of citrus juice coumarins, furanocoumarins and methoxylated flavones using solid phase extraction and HPLC with photodiode array and fluorescence detection. Food Chemistry 2019, 271, 29-38.

2018

• Hung, W. L. Wang, Y. 2018 September. A targeted mass spectrometry-based metabolomics approach toward the understanding of host responses to Huanglongbing. Journal of Agricultural and Food Chemistry. 66, 10651-10661.

• Feng, S., Niu, L., Suh, J. H., Hung, W. L., Wang, Y. Comprehensive metabolomics analysis of mandarins (Citrus reticulata) as a tool for variety, rootstock and grove discrimination. Journal of Agricultural and Food Chemistry 2018, 66, 10317-10326

• Hung, W. L.; Wang, S.; Sang, S., Wan, X., Wang, Y., Ho, C. T. Quantification of ascorbyl adducts of epigallocatechin gallate and gallocatechin gallate in bottled tea beverages. Food Chemistry 2018, 246, 246-252.

• Tung, Y. C., Hsieh, T. H., Yang, M. J., Hung, W. L., Ho, C. T., Pan, M. H. The effects of the extract of oolong tea and its metabolites from Andraca theae in high fat diet induced obese Wistar rat. Food Science and Human Wellness. 2018, 7, 120-124.

• Hung, W. L.; Wang, Y. Metabolite profiling of Candidatus Liberibacter infection in Hamlin sweet oranges. Journal of Agricultural and Food Chemistry 2018, 66, 3983-3991.

• Hung, W. L.; Chang, W. S.; Lu, W. C.; Wei, G. J.; Wang, Y.; Ho, C. T.; Hwang, L. S. Pharmacokinetics, bioavailability, tissue distribution and excretion of tangeretin in rat. Journal of Food and Drug Analysis 2018, 26, 849-857.

• Wang, S.; Suh, J. H.; Hung, W. L.; Zheng, X.; Wang, Y.; Ho, C. T. Use of UHPLC-TripleQ with synthetic standards to profile anti-inflammatory hydroxycinnamic acid amides in root barks and leaves of Licium barbarum. Journal of Food and Drug Analysis 2018, 26, 572-582.

2017

• Hung, W. L.; Yang, G.; Wang, Y. C.; Chiou, Y. S.; Tung, Y. C.; Yang, M. J.; Wang, B. N.; Ho, C. T.; Wang, Y.; Pan, M. H. Protective effects of theasinensin A against carbon tetrachloride-induced liver injury in mice. 2017. Food & Function, 2017, 8, 3276-3287.

• Suh, J. H.; Niu, Y. S.; Hung, W. L.; Ho, C. T.; Wang, Y. Lipidomic analysis for carbonyl species derived from fish oil using liquid chromatography-tandem mass spectrometry. Talanta. 31-42.

• Hung, W. L.; Suh, J. H.; Wang, Y. 2017 Jan. Chemistry and health effects of furanocoumarins in grapefruit. 2017. Journal of Food and Drug Analysis, 2017, 25, 71-83.

2016

• Hung, W. L.; Hwang, L. S.; Shahidi, F.; Pan, M. H.; Wang, Y.; Ho, C. T. Endogenous formation of trans fatty acids: Health implications and potential dietary intervention. 2016. Journal of Functional Foods, 2016, 25. 14-24.

• Hung, W. L.; Liao, C. D.; Lu, W. C.; Ho, C. T.; Hwang, L. S.  Lignan glycosides from sesame meal exhibit higher oral bioavailability and antioxidant activity in rat after nano/submicrosizing. Journal of Functional Foods, 2016, 23. 511-522.

• Tung, Y. C.; Li, S.; Huang, Q.; Hung, W. L.; Ho, C. T.; Wei, G. J.; Pan, M. H. 5-Demethylnobiletin and 5-Acetoxy-6,7,8,3’,4’-pentamethoxyflavone suppress lipid accumulation by activating the LKB1-AMPK pathway in 3T3-L1 preadipocytes and high fat diet-fed C57BL/6 mice. 2016. Journal of Agricultural and Food Chemistry, 2016, 64, 3196-3205.

• Hung, W. L.; Hsu, B. Y.; Tung, Y. C.; Ho, C. T.; Hwang, L. S. Inhibitory effects of antioxidant vitamins against thiyl radical-induced trans fatty acid formation in PC-12 cells. Journal of Functional Foods, 2016, 21, 212-222.

2015​

• Weerawatanakorn, M.; Hung, W. L.; Pan, M. H.; Li, S.; Li, D.; Wan, X.; Ho, C. T. Chemistry and health beneficial effects of oolong tea and theasinensins. Food Science and Human Wellness, 2015, 4, 133-146.

• Hung, W. L.; Liu, C. M.; Lai, C. S.; Ho, C. T.; Pan, M. H.  Inhibitory effect of garcinol against 12-O-tetradecanoylphorbol 13-acetate-induced skin inflammation and tumorigenesis in mice. Journal of Functional Foods, 2015, 18, 432-444.

• Hsu, B. Y., Hung, W. L.; Ho, C. T.; Cheng, I. H.; Hwang, L. S. Protective effects of sesamol and ferulic acid on the formation of endogenous trans-arachidonic acid in hAPP J20 mice. Journal of Functional Foods, 2015, 16, 378-385.

2014

• Hung, W. L.; Cheng, A. C.; Yang, C. C.; Tsai, M. L.; Ho, C. T.; Pan, M. H. Protective effects of garcinol on dimethylnitrosamine-induced liver fibrosis in rats. Food & Function, 2014, 5, 2883-2891.

2013​

• Hung, W. L.; Lu, C. H.; Liao, C. D.; Hwang, L. S. Safety evaluation of nano/submicro-sized lignan glycosides from sesame meal. 2013. Food Control, 2013 30, 129-136.

2011

• Hung, W. L.; Ho, C. T.; Hwang, L. S. Inhibitory activity of natural occurring antioxidants on thiyl radical-induced trans-arachidonic acid formation. 2011 February. Journal of Agricultural and Food Chemistry, 2011 59, 1968-1973.

2010

• Liao, C. D.; Hung, W. L.; Jan, K. C.; Yeh, A. I.; Ho, C. T.; Hwang, L. S. Nano/sub-microsized lignan glycosides from sesame meal exhibit higher transport and absorption efficiency in Caco-2 cell monolayer. Food Chemistry, 2010, 119, 896-902.

• Liao, C. D.; Hung, W. L.; Lu, W. C.; Jan, K. C.; Shih, D. Y.; Yeh, A. I.; Ho, C. T.; Hwang, L. S. Differential tissue distribution of sesaminol triglucoside and its metabolites in rats fed with lignan glycosides from sesame meal with or without nano/Submicrosizing. 2010 January. Journal of Agricultural and Food Chemistry, 2010, 58, 563-569.   

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